Application Notes Archive

The Benefits of Particle Counting with the HandiLaz® Mini II Handheld Particle Counter

Modern manufacturing frequently requires clean environments that are designed, constructed, and sustained to enable the highest yields possible while also hitting predictable throughput targets. This commonly involves achieving a specified cleanroom classification to establish the level of cleanroom performance, and subsequent sustaining efforts that are efficient and nimble. Having the right particle detection equipment for this application is necessary to accomplish these tasks.

High-Purity Process Chemical
Particle Contamination Control

High-Purity Process Chemical Particle Contamination Control has become increasingly complex due to nanometer technology. As semiconductor devices become increasingly complex, and the critical particle size for today’s leading-edge technology nodes decreases into the sub-10 nm size-range, the control and mitigation of potentially yield-impacting particle contamination at the smallest possible particle size becomes ever more crucial. Until recently, there has been a significant sensitivity gap between the critical particle size and the detection limit of traditional chemical particle counters. This paper covers solutions…

contamination control strategy for a fill line

How to Build a Contamination Control Strategy: Considerations and Steps

Mass-produced pharmaceuticals have come far since the industrial manufacturing of synthetic drugs at the end of the 19th century with rapid advancement in technology, process control, and sterility requirements. Yet even as improvements to Pharma develop, recalls still occur with regularity and their significant impact on both the manufacturer and consumer are why worldwide regulation of the industry is so enforced. Environmental monitoring (EM) is one facet of the greater picture of current good manufacturing practices (cGMPs) that has been standardized for the safety of human health.

Contamination Control Strategy (CCS) Build – Questions and Answers

Answers to questions asked during the webinar “Considerations and Steps for Building a Contamination Control Strategy”. Many questions were asked about contamination monitoring requirements in cleanrooms and sampling placement pertaining to process design.